BioBasic/BAFF (B-cell Activating Factor)/5ug/RC214-15
市场价:
¥1427.80
美元价:
713.90
联系Q Q:
3392242852
电话号码:
4000-520-616
电子邮箱:
info@ebiomall.com
商品介绍
Product Description:BAFF (B-cell Activating Factor): B-cell activating factor (BlyS), also known as BAFF, TALL-1, TNAK, and zTNF4, is a TNF ligand superfamily member and has been designated TNFSF13B. Produced by macrophages, dendritic cells, and T lymphocytes, BAFF promotes the survival of B cells and is essential for B cell maturation. BAFF binds to three TNF receptor superfamily members: B-cell maturation antigen (BCMA/TNFRSF17), transmembrane activator and calcium-modulator and cyclophilin ligand interactor (TACI/TNFRSF13B) andBAFF receptor (BAFF R/BR3/TNFRSF 13C). These receptors are type III transmembrane proteins that lack a signal peptide. Whereas TACI and BCMA bind BAFF and another TNF superfamily ligand, APRIL(a proliferation-inducing ligand), BAFF R selectively binds BAFF. The BAFF R extracellular domain lacks the TNF receptor canonical cysteine-rich domain (CRD) and contains only a partial CRD with four cysteine residues. Human and mouse BAFF R share 56% aa sequence identity. BAFF R is highly expressed in spleen, lymph node and resting B cells. It is also expressed at lower levels in activated B cell, in resting CD4+ T cells, in thymus and peripheral blood leukocytes. , UnitProt ID: Q9Y275
Number of Containers:1
Refrigeration Requirements:Freezer
Shipping Conditions:ICE
UNSPSC Code:41116127
UNSPSC Category:Other Cytokines and Chemokines
品牌介绍
Bio Basic Inc.是一家生命科学研究支持公司,成立于加拿大多伦多-总部位于安大略省万锦市和纽约阿默斯特。在Bio Basic,我们相信实验室服务和消耗品可以而且应该负担得起。我们直接制造基因,寡核苷酸,提取试剂盒,PCR试剂和许多其他研究必需品。我们的制造和供应链网络使我们能够提供业内最实惠的价格,而不会影响质量。科学研究的进步涉及许多阶段的漫长而艰辛的旅程。我们认为,通过支持科学研究的初始阶段(也称为“基础研究”),可以为整个过程的成功奠定重要基础。当科学产品和服务的成本上涨时,基础科学研究遭受的损失最大,这就是为什么我们的使命是促进基础科学研究。现在,支持基础研究将使将来的应用研究成功。